Warner Brothers wanted a box office star and Arnold Schwarzenegger was batted around at one point, which is weird for a variety of reasons, though a host jokes he could have pulled off the Laura Linney cheating scenes; both Warren Beatty and Kevin Costner were considered, and Beatty took it seriously enough that after deciding not to do it he brought Dave to Ivan Reitman, which is how Reitman got the movie.
Costner is interesting but one voice doesn't think it works; he had the most power of his career right around then and basically plays Bob Alexander in 13 Days (as transcribed), so he has some interest in the executive branch; Kevin Kline almost turned it down because he thought the character was too close to his Fish Called Wanda character, which none of the hosts can see.
Casting what-ifs are blown early: this was almost a Robin Williams movie, which is 90% likely a disaster and 10% likely a reined-in Dead Poets Society performance; Kevin Kline being such a good and subtle actor keeps the ridiculous premise from becoming a circus show of clown ideas, whereas Williams's big expressive face riding that pig would make you ask what ridiculous movie this is, and how could two people look like Robin Williams.
Roger Ebert came through with three and a half stars, writing that this movie is more proof that it isn't what you do, it's how you do it, and that Ivan Reitman's direction and Gary Ross's screenplay use intelligence and warm-hearted sentiment to make wonderful light-hearted entertainment.
A host jokes that the it-isn't-what-you-do axiom could apply to Ebert's entire career as discussed on this show, that the archives don't lie, and that it isn't about two stars but what's inside the two stars.
Todd Phillips for one host: he is bigger than Apatow by box office though nobody thinks of him that way, his next film is a Joker movie, and he will probably be Oscar-nominated this year as a producer of A Star Is Born with partner Bradley Cooper; Cooper's Toronto premiere speech crediting Phillips's note of belief made Cooper Ali (as transcribed) and Phillips Jackson.
The Ringer ran a Mike Powell profile of Phillips at launch in summer 2016 with Cooper and others quoted going to bat for him; his real skill, learned from Ivan Reitman, is choosing people at the right time, as with Ferrell and writing for Vaughn; the vote is Todd Phillips.
Another host goes Vince Vaughn for variety, calling him incredible with every line quotable.
Tic-tac-toe, three different answers; sorry Luke Wilson; a joke about whether a note saying nobody believes in you like I believe in you should have been given in 2012 to the host then running the Triangle at Grantland.