The hedged blanket answer is probably everybody in the movie except James Remar, whose peak was 48 Hours or arguably Sex and the City, with Mortal Kombat 2 floated as a joke.
Lynn Thigpen's peak is Where in the World Is Carmen Sandiego, Sesame Street or Lean on Me; Terry Michos's might be his newscaster gig in Wappinger Falls.
Remar lived in one host's LA neighborhood; another interviewed him and found him the most straight-talking, hard-edged subject ever, swearing mid-sentence for no reason, recounting 'you got to remember when you're an actor, it's a lot of work'.
Mercedes Rue (as transcribed), the undercover cop, became somebody and was Oscar-nominated, the hosts think for The Fisher King, and played the mom in Big; she is hard to recognize here because she is so young.
The novel's characters were not white and Paramount refused an all-black cast; Tony Danza was to play Vermin before taking Taxi, so Terry Michos was cast
In the book none of the characters were white, and Walter Hill has said Paramount did not want an all-black cast for commercial reasons; the hosts would like to see that movie.
Tony Danza was supposed to be Vermin, the slick Italian-American comic-relief guy, but took the sitcom Taxi; Terry Michos got the part and is now a news anchor in Wappinger Falls, New York.